Several epidemiological studies suggest that traumatic brain injury (TBI) is a risk fac-
tor for dementia, particularly for Alzheimer’s Disease (AD), although a signifcant as-
sociation has not always been observed. Defning the factors that may or may not
link TBI to dementia has important considerations given the high incidence of sport
and motor vehicle related head injuries in the developed world and the high preva-
lence of AD in the aged population. Understanding the associations between these
two enormous unmet medical needs will have profound implications for post-injury
management as well as for the medico-legal system. Here we review existing studies
that support an association between antecedent TBI and increased dementia risk. We review the diverse spectrum of TBI severity and discuss potential mechanisms by which brain injury may trigger a cascade of events that could lead to dementia.
We also note the limitations of the current studies and highlight the importance of future research designed specifcally to determine whether TBI infuences the natural history of AD, particularly with respect to biomarkers.
Seguir leyendoexpand_more
Título : Journal of Neurology and Neuroscience: Brain injury and dementia:
Is there a connection?
EAN : cdljn21716612
Editorial : Fundación de Neurociencias
Fecha de publicación
: 3/4/12
Formato : PDF
Tamaño del archivo : 759.09 kb
Protección : Adobe DRM
El libro electrónico Journal of Neurology and Neuroscience: Brain injury and dementia:
Is there a connection? está en formato PDF
protegido por Adobe DRM
- highlight_off
Este eBook no es compatible para su lectura en las aplicaciones Vivlio de iOs y Android.
- highlight_off
Este eBook no es compatible para leer en My Vivlio.
- highlight_off
Este eBook no es compatible para su lectura en el lector Vivlio.
- check_circle
Este eBook requerirá software propietario para ser leído en el e-reader. Además, el lector electrónico no permite adaptar el tamaño de letra a este formato.
¿Quieres leer en un eReader de otra marca? Sigue
nuestra guía.
Edición en Inglés
Conectarme
Mi cuenta